BIOMEDICINE: Precipitating an Invasion

An Update on Statistical Boosting in Biomedicine

Statistical boosting algorithms have triggered a lot of research during the last decade. They combine a powerful machine learning approach with classical statistical modelling, offering various practical advantages like automated variable selection and implicit regularization of effect estimates. They are extremely flexible, as the underlying base-learners (regression functions defining the typ...

Earthworm-An alternative approach to biomedicine

Big data in biomedicine - An NIH perspective

Philip E. Bourne National Institutes of Health Biomedical research is becoming increasingly data driven, analytical and hence digital. In recognition of this evolution NIH has established the Office for Data Science with trans NIH responsibility for maximizing the value of this digital enterprise. This effort brings together communities, policy changes and new infrastructure to be applied to ex...

Exploring Serendipity's Precipitating Conditions

Serendipity is generally characterized as a sagacious, unsought discovery. Innovations and advances in science and engineering such as penicillin and Teflon as a result of interactions with tangible engineered and natural phenomena are often labeled serendipitous. Serendipity also results from more conceptual interactions with information, knowledge, and ideas. But how does serendipity emerge w...

Tropical Biomedicine